1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Antibody
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Description
AGPAT1 Antibody is a Rabbit Polyclonal against AGPAT1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Immunogen: 1-acylglycerol-3-phosphate O-acyltransferase 1(lysophosphatidic acid acyltransferase, alpha) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | IHC: 1/20 - 1/200, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 32 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99943 |
| Gene ID | 10554 |
| OMIM | 603099 |
| Alias | 1-AGPAT1,G15,LPAAT-alpha |
| Background | Antibody anti-AGPAT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
AGPAT1 is a key enzyme in the phospholipid biosynthesis pathway, catalyzing the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA) by acylating the sn-2 position of LPA. Structurally, AGPAT1 is an integral membrane protein localized to the endoplasmic reticulum (ER), where it participates in the synthesis of phospholipids and triglycerides. It plays an essential role in cell membrane formation, lipid signaling, and energy storage. AGPAT1 is ubiquitously expressed and is critical for maintaining cellular lipid homeostasis. Dysregulation of AGPAT1 is associated with metabolic disorders and diseases linked to impaired phospholipid metabolism, such as insulin resistance and lipodystrophy.
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