Adhesion Molecule With Ig Like Domain Protein 1 (AMIGO1) Antibody
299€ (100 µl)
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935106861
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name
Adhesion Molecule With Ig Like Domain Protein 1 (AMIGO1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130635
tested applications
WB, IHC, IF/ICC
Description
AMIGO1 Antibody is a Rabbit Polyclonal against AMIGO1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Adhesion Molecule With Ig Like Domain Protein 1 (AMIGO1) Immunogen: abx650826 -Recombinant AMIGO1 (Gly28-Thr372) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 0.97 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.4, containing 0.02% Sodium azide, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86WK6 |
| Alias | AMIGO-1,Alivin-2 |
| Background | Antibody anti-AMIGO1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
AMIGO1 is a cell adhesion molecule belonging to the AMIGO family, which is involved in neuronal development, axon guidance, and synaptic formation. AMIGO1 is highly expressed in the central nervous system (CNS), where it mediates neurite outgrowth and contributes to axon fasciculation during neural circuit formation. It interacts with other cell adhesion molecules and extracellular matrix proteins to promote cell-cell and cell-extracellular interactions critical for proper neuronal connectivity. AMIGO1 has also been implicated in synaptic plasticity and stability, supporting learning, memory, and neural repair. Dysregulation of AMIGO1 has been associated with neurodegenerative diseases such as Alzheimer’s disease, where axonal damage and synaptic dysfunction are observed. In addition to its neuronal roles, emerging evidence suggests that AMIGO1 may influence tumor progression, as its expression can promote cell migration and invasion in certain cancers. This highlights its dual significance in both neural development and disease pathology.
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Human Adhesion Molecule With Ig Like Domain Protein 1 (AMIGO1) Protein
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