ALK Tyrosine Kinase Receptor (ALK) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
ALK Tyrosine Kinase Receptor (ALK) Antibody is a Rabbit polyclonal antibody for the detection of Human ALK Tyrosine Kinase Receptor (ALK).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ALK Tyrosine Kinase Receptor (ALK) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UM73 |
| Gene ID | 238 |
| NCBI Accession | NP_004295.2 |
| Alias | CD246 |
| Background | Antibody anti-ALK |
| Status | RUO |
Descripción
Related Products
Human ALK (Anaplastic lymphoma kinase) ELISA Kit
Ver Producto
Mouse Anti-ALK (ALK tyrosine kinase receptor) antibody ELISA Kit
Ver Producto
ALK antibody
Anaplastic Lymphoma Kinase (ALK), also known as CD246, is a 220 kDa transmembrane glycoprotein that is primarily expressed in the developing nervous system. ALK contains one LDL Receptor (LDLR) class A domain, two meprin/A5-protein/PTPmu (MAM) domains, and a cytoplasmic kinase domain. Chromosomal translocation involving ALK and the nucleolar NPM protein result in a cytoplasmic fusion protein that exists as a dimer. The kinase domain in NPM-ALK is constitutively active and participates in cellular transformation. ALK translocations are found in a variety of tumors. Within the extracellular domain, human and mouse ALK share 88% amino acid sequence identity.
Ver Producto