Alpha-1-Acid Glycoprotein 2 (ORM2) Antibody
273€ (100 µl)
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935106861
info@markelab.com
name
Alpha-1-Acid Glycoprotein 2 (ORM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx101108
tested applications
WB, IHC
Description
Polyclonal Antibody to Orosomucoid 2 (ORM2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Alpha-1-Acid Glycoprotein 2 (ORM2) Immunogen: abx068395 - Recombinant ORM2 (Gln19-Ala207) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Mouse |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07361 |
| Alias | AGP2,AGP-B,AGP-B,Orosomucoid 2,OMD 2,Orosomucoid-2 |
| Background | Antibody anti-ORM2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Alpha-1-acid glycoprotein 2 (ORM2), also known as orosomucoid 2, is a major acute-phase protein predominantly produced in the liver and secreted into the bloodstream. ORM2 belongs to the lipocalin family, a group of small proteins characterized by their ability to bind and transport small hydrophobic molecules, including drugs, steroids, and lipids. As an acute-phase reactant, ORM2 levels increase significantly in response to inflammation, infection, trauma, or other physiological stresses, playing a critical role in the systemic inflammatory response.ORM2 is closely related to ORM1 (Alpha-1-acid glycoprotein 1), with both proteins sharing high sequence and structural homology. Together, they constitute the majority of the alpha-1-globulin fraction in human plasma. ORM2 has immunomodulatory functions, influencing immune cell activity, vascular permeability, and interactions between cytokines. Additionally, ORM2 is significant in pharmacology because it binds to various drugs, impacting their bioavailability and pharmacokinetics.
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Mouse Alpha-1-Acid Glycoprotein 2 (ORM2) Protein
Mouse Orosomucoid 2 (ORM2) is a recombinant Mouse protein expressed in E. coli.
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