Alpha 1B Adrenergic Receptor (ADRA1B) Antibody

Este producto es parte de ADRA1 - Alpha-1A(1B) (1C) Adrenergic receptor
Product Graph
377€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Alpha 1B Adrenergic Receptor (ADRA1B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230178
tested applications
ELISA, WB

Description

ADRA1B Antibody is a Rabbit Polyclonal against ADRA1B.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Alpha 1B Adrenergic Receptor (ADRA1B)
Immunogen: adrenergic, alpha-1B-, receptor
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 2 mg/ml
Recommended Dilution
WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 50 kDa
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P35368
Gene ID
147
OMIM
104220
Alias
ADRA1B,ADRA1,ALPHA1BAR,adrenergic alpha 1B receptor
Background
Antibody anti-ADRA1B
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

The adrenergic receptors are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter adrenaline (epinephrine) and noradrenaline (norepinephrine). The alpha-1 adrenergic receptor (ADRA1) is one subtype of adrenergic receptors, and it has three main subtypes: Alpha-1A (ADRA1A), Alpha-1B (ADRA1B), and Alpha-1D (ADRA1D). ADRA1B encodes the α1B-adrenergic receptor, predominantly expressed in the liver, heart, and cerebral blood vessels.

Related Products

FNab00178

ADRA1B antibody

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

Ver Producto
abx015217

Alpha 1B Adrenergic Receptor (ADRA1B) Antibody

Rabbit polyclonal antibody against ADRA1B protein. Immunogen region is internal.

Ver Producto
abx031294

Alpha 1B Adrenergic Receptor (ADRA1B) Antibody

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, 1B and 1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Ver Producto