alpha 2-Antiplasmin (SERPINF2) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
alpha 2-Antiplasmin (SERPINF2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432316
tested applications
P-ELISA, WB, IHC, IF/ICC, FCM
Description
alpha 2-antiplasmin Antibody is a Goat Polyclonal antibody against alpha 2-antiplasmin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: alpha 2-Antiplasmin (SERPINF2) Immunogen: abx615632 - Internal region: C-KDFLQSLKGFPRGDK |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC, IF/ICC, FCM |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 5345 |
| NCBI Accession | NP_000925.2, NP_001159393.1 |
| Alias | AAP,API,PLI,A2AP,alpha2AP,Alpha-2-antiplasmin,Alpha-2-AP,Alpha-2-plasmin inhibitor,Serpin F2 |
| Background | Antibody anti-SERPINF2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
SERPINF2, also known as alpha-2 antiplasmin (A2AP), is a crucial member of the serpin (serine protease inhibitor) family. It plays a vital role in regulating the fibrinolytic system by inhibiting plasmin, the enzyme responsible for breaking down fibrin clots. As part of the serpin superfamily, SERPINF2 helps to maintain hemostasis by preventing excessive clot breakdown, ensuring that clots remain stable during wound healing and tissue repair. First characterized in the 1970s, SERPINF2 has since been extensively studied for its role in clot stabilization and its involvement in various bleeding disorders and thrombotic conditions. It is primarily synthesized in the liver and circulates in the plasma, where it acts as a major inhibitor of fibrinolysis.
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