Alpha-2-Heremans Schmid Glycoprotein (AHSG) Antibody
273€ (100 µl)
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935106861
info@markelab.com
name
Alpha-2-Heremans Schmid Glycoprotein (AHSG) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx103795
tested applications
WB, IHC
Description
Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Alpha-2-Heremans Schmid Glycoprotein (AHSG) Immunogen: abx065248 - Recombinant aHSG (Ala19-Phe250) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Mouse |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29699 |
| Alias | AHSG A2HS,alpha-2-HS-glycoprotein,Fetuin A |
| Background | Antibody anti-AHSG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Fetuin-A, also known as alpha-2-HS-glycoprotein (AHSG), is a circulating glycoprotein primarily synthesized by the liver. It plays diverse roles in the body, including regulation of mineral metabolism, inhibition of pathological calcification, modulation of insulin signaling, and regulation of inflammation. Fetuin-A functions as an inhibitor of ectopic mineralization by forming soluble complexes with calcium and phosphate ions, preventing their precipitation in soft tissues. Additionally, fetuin-A interacts with various receptors and signaling pathways, influencing insulin sensitivity and glucose homeostasis. Dysregulation of fetuin-A levels has been implicated in metabolic disorders such as diabetes, cardiovascular disease, and chronic kidney disease. Understanding the molecular mechanisms underlying fetuin-A function provides insights into its roles in health and disease, offering potential therapeutic targets for metabolic and cardiovascular conditions. Ongoing research continues to elucidate the multifaceted functions of fetuin-A and its implications for human health
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