Aminopeptidase N (ANPEP) Antibody

442€ (200 µl)
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name
Aminopeptidase N (ANPEP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430199
tested applications
P-ELISA, WB
Description
Aminopeptidase N / CD13 (ANPEP) Antibody is a Goat Polyclonal antibody against CD13.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Aminopeptidase N (ANPEP) Immunogen: abx617239 - Internal region (near C-Terminus): C-QLEQFKKDNEET |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15144 |
| Gene ID | 290 |
| NCBI Accession | NP_001141.2 |
| OMIM | 151530 |
| Alias | APN,AP-M,AP-N,CD13,LAP1,P150,PEPN,Hapn,GP150,Aminopeptidase N,Alanyl aminopeptidase,Microsomal aminopeptidase,Myeloid plasma membrane glycoprotein |
| Background | Antibody anti-ANPEP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ANPEP, also known as alanyl aminopeptidase or aminopeptidase N (APN), is a key membrane-bound enzyme that plays a significant role in the hydrolysis of peptides. The gene ANPEP encodes this enzyme, which is expressed predominantly on the surface of epithelial cells in the small intestine, kidney, and other tissues, and also in certain immune cells such as monocytes, macrophages, and granulocytes. ANPEP is classified as a zinc metalloprotease, which means that its catalytic activity depends on a zinc ion in its active site. In the small intestine, ANPEP facilitates the final stages of protein digestion by cleaving neutral amino acids from the N-terminus of oligopeptides. Beyond its digestive role, ANPEP also participates in various physiological processes, including antigen processing, angiogenesis, immune response regulation, and the inflammatory response
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