ADM antibody
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935106861
info@markelab.com
name
ADM antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00181
tested applications
ELISA, IHC, WB
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | adrenomedullin (ADM) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 7 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P35318 |
| Gene ID | 133 |
| Alias | AM,PAMP |
| Background | Antibody anti-ADM |
| Status | RUO |
| Note | Mol. Weight 7 kDa |
Adrenomedullin (ADM) is a peptide hormone that is primarily secreted by various tissues, including the adrenal medulla, vascular endothelium, heart, lungs, and kidneys. Adrenomedullin is a 52-amino acid peptide hormone derived from a larger precursor protein called preproadrenomedullin. It belongs to the calcitonin gene-related peptide (CGRP) family and shares structural similarities with calcitonin and calcitonin gene-related peptide. Adrenomedullin plays a crucial role in regulating vascular tone, blood pressure, and cardiovascular homeostasis by promoting vasodilation and inhibiting vasoconstriction. Additionally, adrenomedullin exhibits anti-inflammatory, anti-apoptotic, and angiogenic properties, contributing to tissue protection and repair.Adrenomedullin binds to specific receptors known as adrenomedullin receptors (ADMR), which are coupled to G proteins
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