APAF1 antibody
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935106861
info@markelab.com
name
APAF1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00470
tested applications
ELISA, WB, IHC, IP, IF
Description
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9(Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | apoptotic peptidase activating factor 1 (APAF1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 140 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O14727 |
| Gene ID | 317 |
| Alias | Apoptotic protease-activating factor 1 (APAF-1),APAF1,KIAA0413 |
| Background | Antibody anti-APAF1 |
| Status | RUO |
| Note | Mol. Weight 140 kDa |
Descripción
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