CARD6 antibody
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Name
CARD6 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab01270
Tested Applications
ELISA, WB, IHC
Description
May be involved in apoptosis.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | caspase recruitment domain family, member 6 (CARD6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 130kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BX69 |
| Gene ID | 84674 |
| Alias | CINCIN1 |
| Background | Antibody anti-CARD6 |
| Status | RUO |
| Note | Mol. Weight 130 kDa |
Background
CARD6 is part of the caspase recruitment domain family of proteins and is involved in the regulation of immune cell signaling, particularly in response to stress and inflammation. CARD6 is expressed in various tissues, including immune cells, and is believed to play a role in controlling NF-κB signaling pathways. While it shares the CARD domain with other family members like CARD9 and CARD8, CARD6 has distinct functions, including its involvement in apoptosis and inflammatory responses. It can modulate both pro-inflammatory and anti-inflammatory signaling, making it an important protein in the balance of immune activation. In certain conditions, such as chronic inflammatory diseases, the activity of CARD6 can become dysregulated, contributing to excessive inflammation. Further understanding of CARD6’s role in immune signaling may provide insights into therapeutic strategies for diseases involving chronic inflammation and autoimmune disorders.
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