CASP9 antibody
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935106861
info@markelab.com
name
CASP9 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01295
tested applications
ELISA, IF, IHC, IP, WB, FC
Description
Caspase 9, apoptosis-related cysteine protease(CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1; this step is thought to be one of the earliest in the caspase activation cascade. FNab01295 can recognize the pre-and cleaved-caspase 9.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | caspase 9, apoptosis-related cysteine peptidase (CASP9) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 46kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IF, IHC, IP, WB, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P55211 |
| Gene ID | 842 |
| Alias | Caspase-9 (CASP-9),Apoptotic protease Mch-6,Apoptotic protease-activating factor 3 (APAF-3),ICE-like apoptotic protease 6 (ICE-LAP6),Caspase-9 subunit p35,Caspase-9 subunit p10,CASP9,MCH6 |
| Background | Antibody anti-CASP9 |
| Status | RUO |
| Note | Mol. Weight 46 kDa |
Descripción
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