DKK2 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
DKK2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02402
tested applications
ELISA, WB, IHC
Description
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | dickkopf homolog 2 (DKK2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 32 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UBU2 |
| Gene ID | 27123 |
| Alias | Dickkopf-related protein 2 (Dickkopf-2, Dkk-2, hDkk-2),DKK2 |
| Background | Antibody anti-DKK2 |
| Status | RUO |
| Note | Mol. Weight 32 kDa |
Descripción
Related Products
Human DKK2 (Dickkopf-related protein 2) ELISA Kit
Ver Producto
Mouse DKK2 (Dickkopf-related protein 2) ELISA Kit
Ver Producto