GSDMD antibody

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935106861
info@markelab.com
name
GSDMD antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03670
tested applications
ELISA, WB, IHC, IF
Description
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | gasdermin D (GSDMD) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50-53 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P57764 |
| Gene ID | 79792 |
| Alias | Gasdermin-D,Gasdermin domain-containing protein 1,Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD),Gasdermin-D, p13,Gasdermin-D, 13 kDa (13 kDa GSDMD),Gasdermin-D, p40,GSDMD,DFNA5L,GSDMDC1 |
| Background | Antibody anti-GSDMD |
| Status | RUO |
| Note | Mol. Weight 50-53 kDa |
Descripción
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