HSP90AA1 antibody
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935106861
info@markelab.com
name
HSP90AA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09974
tested applications
ELISA, IHC, WB
Description
HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | heat shock protein 90kDa alpha(cytosolic), class A member 1 (HSP90AA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P07900 |
| Gene ID | 3320 |
| Alias | Heat shock protein HSP 90-alpha,Heat shock 86 kDa (HSP 86, HSP86),Lipopolysaccharide-associated protein 2 (LAP-2, LPS-associated protein 2),Renal carcinoma antigen NY-REN-38,HSP90AA1,HSP90A,HSPC1,HSPCA |
| Background | Antibody anti-HSP90AA1 |
| Status | RUO |
| Note | Mol. Weight 100 kDa |
Descripción
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