IDH1 antibody
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935106861
info@markelab.com
name
IDH1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04119
tested applications
ELISA, WB, IHC, IF
Description
IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | isocitrate dehydrogenase 1(NADP+), soluble (IDH1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 1G10 |
| Observed MW | 46kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O75874 |
| Gene ID | 3417 |
| Alias | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH, IDH1),Cytosolic NADP-isocitrate dehydrogenase,IDPc,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,IDH1,PICD |
| Background | Antibody anti-IDH1 |
| Status | RUO |
| Note | Mol. Weight 46 kDa |
Descripción
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