NEFL antibody
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935106861
info@markelab.com
name
NEFL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05710
tested applications
ELISA, WB, IHC, IF
Description
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | neurofilament, light polypeptide (NEFL) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:100 - 1:500; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 72 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P07196 |
| Gene ID | 4747 |
| Alias | Neurofilament light polypeptide (NF-L),68 kDa neurofilament protein,Neurofilament triplet L protein,NEFL,NF68,NFL |
| Background | Antibody anti-NEFL |
| Status | RUO |
| Note | Mol. Weight 68 kDa |
Descripción
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