CDKN2A antibody
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935106861
info@markelab.com
name
CDKN2A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06064
tested applications
ELISA, WB, IF, IP, IHC, FC
Description
CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). FNab06064 reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | cyclin-dependent kinase inhibitor 2A(melanoma, p16, inhibits CDK4) (CDKN2A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 16-18 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP, IHC, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P42771 |
| Gene ID | 1029 |
| Alias | Cyclin-dependent kinase inhibitor 2A,Cyclin-dependent kinase 4 inhibitor A (CDK4I),Multiple tumor suppressor 1 (MTS-1),p16-INK4a (p16-INK4, p16INK4A),CDKN2A,CDKN2,MTS1 |
| Background | Antibody anti-CDKN2A |
| Status | RUO |
| Note | Mol. Weight 16-18 kDa |
Descripción
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