PRKACB antibody
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935106861
info@markelab.com
name
PRKACB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06778
tested applications
ELISA, WB, IHC, IF, IP
Description
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein kinase, cAMP-dependent, catalytic, beta (PRKACB) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 46-55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P22694 |
| Gene ID | 5567 |
| Alias | cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta),PRKACB |
| Background | Antibody anti-PRKACB |
| Status | RUO |
| Note | Mol. Weight 46-55 kDa |
Descripción
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