Apolipoprotein L4 (APOL4) Antibody

442€ (200 µl)
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935106861
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name
Apolipoprotein L4 (APOL4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432354
tested applications
P-ELISA, WB, IHC
Description
APOL4 Antibody is a Goat Polyclonal antibody against APOL4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Apolipoprotein L4 (APOL4) Immunogen: abx615627 - C-Terminus: C-ENLNELTHIHQSLK |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 80832 |
| NCBI Accession | NP_085146.2, NP_663693.1 |
| Alias | APOLIV,Apolipoprotein L-IV,Apolipoprotein L 4,APOL-IV,Apolipoprotein L4 |
| Background | Antibody anti-APOL4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Apolipoprotein L4 (APOL4) is a lesser-studied member of the Apolipoprotein L family and is thought to participate in lipid transport, cellular signaling, and immune modulation. APOL4 is expressed in multiple tissues, including the brain, liver, and immune cells, and localizes to intracellular compartments such as the endoplasmic reticulum and lipid membranes. Like other APOL family members, APOL4 is believed to influence cellular lipid homeostasis, lipid transport pathways, and apoptosis regulation. Its expression is regulated by inflammatory cytokines, suggesting a role in innate immunity and responses to cellular stress. Although the specific biological functions of APOL4 remain unclear, studies indicate that it may contribute to processes such as membrane trafficking, lipid metabolism, and host defense mechanisms against pathogens. Dysregulation of APOL4 expression has been observed in various pathological conditions, including cancers and neurodegenerative diseases, implicating its involvement in cellular survival and disease progression. Further research is needed to fully elucidate APOL4’s functional roles and its potential as a biomarker or therapeutic target in lipid metabolism disorders, immune regulation, and cancer biology.
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