Arrestin Beta 1 (ARRB1) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Arrestin Beta 1 (ARRB1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000951
tested applications
IHC, IF/ICC

Description

ARRB1 Antibody is a Rabbit Polyclonal antibody against ARRB1. Members of ARRB1/beta-ARRB1 protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-ARRB1 system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of ARRB1 have been described.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Arrestin Beta 1 (ARRB1)
Immunogen: Recombinant fusion protein corresponding to human ARRB1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
IHC-P: 1/50 - 1/200, IF/ICC: 1/20 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P49407
Gene ID
408
NCBI Accession
NP_004032.2
Background
Antibody anti-ARRB1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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