ATP Binding Cassette Subfamily E Member 1 (ABCE1) Antibody
442€ (200 µl)
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935106861
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name
ATP Binding Cassette Subfamily E Member 1 (ABCE1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430122
tested applications
P-ELISA, WB
Description
ABCE1 Antibody is a Goat Polyclonal antibody against ABCE1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: ATP Binding Cassette Subfamily E Member 1 (ABCE1) Immunogen: abx269735 - C-Terminus: C-KLNSIKDVEQKK |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 6059, 24015, 361390 |
| NCBI Accession | NP_002931.2, NP_001035809.1 |
| Alias | ABC38,OABP,RLI,RLI1,RNASEL1 |
| Background | Antibody anti-ABCE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ABCE1, also known as the ATP-binding cassette protein E1 or RNase L inhibitor (RLI), is a unique member of the ATP-binding cassette (ABC) transporter superfamily. Unlike most ABC transporters, which are involved in the translocation of various substrates across membranes, ABCE1 primarily functions in the regulation of RNA processing and translation. It is highly conserved across different species, highlighting its fundamental biological importance.ABCE1 works by inhibiting the activity of ribonuclease L, thereby opposing the antiviral properties of ribonuclease L and enabling the virus to synthesize viral proteins. Additionally, ABCE1 has been implicated in influencing tumor cell proliferation
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