ATP Binding Cassette Subfamily F Member 3 (ABCF3) Antibody
292.5€ (200 µl)
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935106861
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name
ATP Binding Cassette Subfamily F Member 3 (ABCF3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431873
tested applications
P-ELISA
Description
ABCF3 Antibody is a Goat Polyclonal antibody against ABCF3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: ATP Binding Cassette Subfamily F Member 3 (ABCF3) Immunogen: abx615619 - Internal region: C-KESRLESSGKNKSYD |
| Host | Goat |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 55324, 27406, 287982 |
| NCBI Accession | NP_060828.2 |
| Alias | EST201864 |
| Background | Antibody anti-ABCF3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ABCF3 is a member of the ABCF subfamily, characterized by its lack of transmembrane domains and its involvement in intracellular processes such as translation regulation and stress response. It is expressed in various tissues, with functions related to ribosomal activity and protein synthesis. ABCF3 is believed to play a role in modulating the translation machinery, particularly under conditions of cellular stress, enabling cells to adapt to adverse environments by selectively synthesizing stress-related proteins. Its role in maintaining protein synthesis is essential for cell survival during environmental challenges, such as oxidative stress or nutrient deprivation. Dysregulation of ABCF3 has been associated with impaired stress tolerance and altered protein homeostasis, which can contribute to pathological conditions such as neurodegenerative diseases or cancer. While its exact molecular mechanisms remain under investigation, ABCF3’s contribution to translation regulation and cellular adaptation highlights its critical role in maintaining cellular integrity and function under both normal and stress conditions.
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