B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody

Este producto es parte de CD79A molecule
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292.5€ (80 µl)

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935106861
info@markelab.com
name
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025317
tested applications
ELISA, WB

Description

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A)
Immunogen: KLH-conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human CD79A.
Host
Mouse
Reactivity
Mouse
Recommended Dilution
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Observed MW
Calculated MW: 25 kDa
Purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P11912
Alias
IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain
Background
Antibody anti-CD79A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

CD79A, also known as Ig-alpha, is a protein encoded by the CD79A gene in humans. It is a crucial component of the B cell receptor (BCR) complex, playing a significant role in B cell development, activation, and signaling. The BCR complex is essential for the adaptive immune response, allowing B cells to recognize and respond to specific antigens. CD79A, along with CD79B (Ig-beta), forms the signaling component of the BCR, transmitting signals from the antigen-bound surface immunoglobulin (Ig) to the cell's interior, initiating a cascade of intracellular events leading to B cell activation, proliferation, and differentiation.

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