Basal Cell Adhesion Molecule (BCAM) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Basal Cell Adhesion Molecule (BCAM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129079
tested applications
WB, IHC
Description
Basal Cell Adhesion Molecule Antibody is a Rabbit Polyclonal against Basal Cell Adhesion Molecule.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Basal Cell Adhesion Molecule (BCAM) Immunogen: abx166711 - Recombinant BCAM (Glu32-His257) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 0.55 mg/ml |
| Recommended Dilution | WB: 0.01-5 µg/ml, IHC: 5-50 µg/ml, IF/ICC (Predicted): 5-50 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P50895 |
| Alias | Basal cell adhesion molecule,Lutheran blood group,AU,LU,B-CAM,CD239,MSK19,Auberger B antigen,B-CAM cell surface glycoprotein |
| Background | Antibody anti-BCAM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Basal Cell Adhesion Molecule (BCAM), also known as Lu antigen or Lutheran antigen, is a type I membrane glycoprotein primarily expressed on the surface of erythrocytes (red blood cells) and other cell types, including endothelial cells and certain epithelial cells. BCAM belongs to the immunoglobulin superfamily of cell adhesion molecules (IgCAMs), which are involved in the adhesion between cells and the extracellular matrix. It is notably involved in the Lutheran blood group system, which plays an important role in blood transfusion medicine. BCAM is an important adhesion molecule that facilitates interactions between cells, as well as between cells and their extracellular matrix (ECM), thus contributing to tissue integrity and signaling processes. BCAM is critical in the endothelial cell junctions and erythrocyte adhesion to endothelial cells, thereby influencing processes like inflammation, vascular permeability, and cell migration. BCAM's expression on erythrocytes links it to important blood group antigens, which have clinical relevance in transfusion medicine, as well as in understanding the molecular mechanisms of various diseases, including autoimmune disorders, inflammatory diseases, and cancers.
Related Products
Human Basal Cell Adhesion Molecule (BCAM) Protein
Human Basal Cell Adhesion Molecule Protein is a recombinant Human protein expressed in E. coli.
Ver Producto