Beta Actin (ACTB) Antibody

208€ (40 µl)
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935106861
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name
Beta Actin (ACTB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx227077
tested applications
IHC
Description
Beta Actin (ACTB) Antibody is a Rabbit Monoclonal antibody for the detection of beta-Actin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Beta Actin (ACTB) Immunogen: Synthetic peptide derived from the C-terminal region of human beta-actin. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC-P: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Clone ID | X592 |
| Purification | Purified from rabbit antiserum by proprietary techniques. |
| Size 1 | 40 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 500 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | 20 mM Tris-HCl, pH 8.0, containing 20 mg/ml BSA and 0.05% NaN3. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 2-8°C. |
| Dry Ice | No |
| UniProt ID | P60709 |
| Alias | BKRNS,BNS,BRWS1,CSMH,DDS1,THC8 |
| Background | Antibody anti-ACTB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ACTB, also known as beta-actin, is a highly conserved protein that serves as a fundamental component of the cytoskeleton in eukaryotic cells. Beta-actin is involved in various cellular processes, including cell structure, motility, and intracellular transport. Beta-actin forms filamentous structures, along with other actin isoforms, which constitute the cytoskeleton. This dynamic network of filaments provides structural support to the cell and is involved in cell shape determination and mechanical stability, motility and migration. It participates in the formation of cell protrusions such as lamellipodia and filopodia, which are essential for cell movement. Beta-actin also plays a role in cell division, where it is involved in cytokinesis, the process of cell division following nuclear division. Furthermore, beta-actin is involved in intracellular transport processes, serving as a track for myosin motor proteins to transport cargo within the cell. This function is essential for the movement of vesicles, organelles, and other cellular components along the cytoskeleton.
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