Beta Actin (ACTB) Antibody
383.5€ (100 µl)
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name
Beta Actin (ACTB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx010457
tested applications
ELISA, WB, IF/ICC, FCM
Description
Beta actin (PS1TP5-binding protein 1), also known as ACTB, PS1TP5BP1, is one of six different actin proteins. Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. Actins are highly conserved proteins that are involved in various types of cell motility, structure, and integrity. Actin is ubiquitously expressed in all eukaryotic cells. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Beta Actin (ACTB) Immunogen: Synthetic peptide corresponding to amino-terminal residues of human beta-Actin, conjugated to KLH. |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Monkey, Hamster |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b |
| Observed MW | 43 kDa |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60709 |
| Gene ID | 60 |
| Alias | BKRNS,BNS,BRWS1,CSMH,DDS1,THC8 |
| Background | Antibody anti-ACTB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ACTB, also known as beta-actin, is a highly conserved protein that serves as a fundamental component of the cytoskeleton in eukaryotic cells. Beta-actin is involved in various cellular processes, including cell structure, motility, and intracellular transport. Beta-actin forms filamentous structures, along with other actin isoforms, which constitute the cytoskeleton. This dynamic network of filaments provides structural support to the cell and is involved in cell shape determination and mechanical stability, motility and migration. It participates in the formation of cell protrusions such as lamellipodia and filopodia, which are essential for cell movement. Beta-actin also plays a role in cell division, where it is involved in cytokinesis, the process of cell division following nuclear division. Furthermore, beta-actin is involved in intracellular transport processes, serving as a track for myosin motor proteins to transport cargo within the cell. This function is essential for the movement of vesicles, organelles, and other cellular components along the cytoskeleton.
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