Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody
377€ (100 µg)
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Name
Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx230922
Tested Applications
ELISA, WB, IF/ICC, IP
Description
BMPR1A Antibody is a Rabbit Polyclonal against BMPR1A.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Bone Morphogenetic Protein Receptor 1A (BMPR1A) Immunogen: bone morphogenetic protein receptor, type IA |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100, IP: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 60 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P36894 |
| Alias | Activin receptor-like kinase 3,ALK3,SKR5,ALK-3,CD292,ACVRLK3,BMPR-1A,Serine/threonine-protein kinase receptor R5 |
| Background | Antibody anti-BMPR1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Bone morphogenetic protein receptor type 1A (BMPR1A) is a receptor for the bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor-beta (TGF-β) superfamily. BMPs are growth factors and cytokines that play critical roles in embryonic development, skeletal formation, organogenesis, and tissue homeostasis. BMPR1A, also known as ALK3 (Activin receptor-like kinase 3), specifically mediates BMP signaling by interacting with BMP ligands to activate intracellular pathways, influencing processes such as cell growth, differentiation, apoptosis, and repair. This receptor is essential for bone and cartilage development and has critical roles in several cell types across various tissues, with particularly strong influence in skeletal, cardiac, and gastrointestinal systems.
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