Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx125495
tested applications
WB
Description
Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Antibody is a Rabbit Polyclonal against ADGRB3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Immunogen: Recombinant fusion protein corresponding to human ADGRB3 |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 55 kDa/171 kDa Observed MW: 180 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60242 |
| Gene ID | 577 |
| NCBI Accession | NP_001695.1 |
| Alias | ADGRB3,BAI3 |
| Background | Antibody anti-ADGRB3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ADGRB3, known as BAI3, is a GPCR highly expressed in the brain, where it regulates synaptic development and neuronal connectivity. It plays a role in dendritic arborization and synapse formation, supporting neuronal circuitry and communication. ADGRB3 interacts with proteins involved in synaptic organization and phagocytosis, contributing to the removal of apoptotic neurons and cellular debris. Dysregulation of ADGRB3 has been associated with autism spectrum disorders and other neurodevelopmental conditions due to its role in synaptic refinement. Additionally, it is implicated in vascular homeostasis, although its angiogenic functions are less defined compared to ADGRB1. ADGRB3’s dual involvement in synaptic and vascular processes highlights its importance in neurovascular coupling and overall brain health.
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