Caspase recruitment domain-containing protein 6 (CARD6) Antibody (HRP)
260€ (50 µl)
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Name
Caspase recruitment domain-containing protein 6 (CARD6) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx348832
Tested Applications
ELISA
Description
Caspase recruitment domain-containing protein 6 (CARD6) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human CARD6.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Caspase recruitment domain-containing protein 6 (CARD6) Immunogen: Recombinant Human Caspase recruitment domain-containing protein 6 protein (666-930 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BX69 |
| Gene ID | 84674 |
| Alias | CINCIN1 |
| Background | Antibody anti-CARD6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CARD6 is part of the caspase recruitment domain family of proteins and is involved in the regulation of immune cell signaling, particularly in response to stress and inflammation. CARD6 is expressed in various tissues, including immune cells, and is believed to play a role in controlling NF-κB signaling pathways. While it shares the CARD domain with other family members like CARD9 and CARD8, CARD6 has distinct functions, including its involvement in apoptosis and inflammatory responses. It can modulate both pro-inflammatory and anti-inflammatory signaling, making it an important protein in the balance of immune activation. In certain conditions, such as chronic inflammatory diseases, the activity of CARD6 can become dysregulated, contributing to excessive inflammation. Further understanding of CARD6’s role in immune signaling may provide insights into therapeutic strategies for diseases involving chronic inflammation and autoimmune disorders.
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