Caspase Recruitment Domain Family Member 10 (CARD10) Antibody
221€ (50 µg)
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Name
Caspase Recruitment Domain Family Member 10 (CARD10) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx326077
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
CARD10 Antibody is a Rabbit Polyclonal against CARD10.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Caspase Recruitment Domain Family Member 10 (CARD10) Immunogen: Synthesized peptide derived from the Internal region of human CARD 10. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BWT7 |
| Gene ID | 29775 |
| Alias | CARD-containing MAGUK protein 3, BIMP1, CARMA3, IMD89 |
| Background | Antibody anti-CARD10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CARD10 is a protein that is part of the caspase recruitment domain (CARD) family. Like other members of this family, it plays a role in mediating immune responses by acting as an adaptor protein in cell signaling pathways. CARD10 is involved in the regulation of the NF-κB pathway, a crucial signaling pathway for immune cell activation, inflammation, and cellular survival. CARD10 is also involved in the regulation of apoptosis, and its function helps maintain immune homeostasis by controlling both cell survival and death. Dysregulation of CARD10 may contribute to various immune-related diseases, including cancers and autoimmune disorders, due to improper regulation of NF-κB and apoptosis. Researchers are investigating how CARD10 could be targeted in therapeutic interventions, especially in diseases characterized by chronic inflammation or immune dysfunction.
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