Chicken Leptin Receptor (LEPR) Protein
338€ (20 µg)
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Name
Chicken Leptin Receptor (LEPR) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx262060
Tested Applications
SDS-PAGE
Description
Leptin Binding Domain Protein is a recombinant cytokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Leptin Receptor (LEPR) |
| Assay Type | Activity: Not tested |
| Origin | Chicken |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 99% (SDS-PAGE and SEC-HPLC) |
| Size 1 | 20 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | OBR,OB-R,CD295,LEP-R,LEPRD,HuB219,OB receptor |
| Background | Protein LEPR |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
The leptin receptor (LEPR) is a cell surface receptor that plays a central role in energy homeostasis, metabolism, and body weight regulation. LEPR is the receptor for leptin, a hormone primarily secreted by adipose (fat) tissue that signals satiety and energy sufficiency to the brain. Leptin and its receptor are fundamental to regulating food intake, body weight, and energy expenditure. When leptin binds to LEPR, it triggers a cascade of intracellular signals that inform the central nervous system about the body's energy reserves, particularly in the hypothalamus, which then influences appetite suppression, metabolism, and other endocrine functions. LEPR is essential in maintaining homeostatic control over body mass, as dysregulation or mutations in the leptin receptor pathway can lead to obesity, diabetes, and metabolic syndrome.
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