Coronin 3 (CORO1C) Antibody
442€ (200 µl)
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name
Coronin 3 (CORO1C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430879
tested applications
P-ELISA, WB
Description
Coronin 3 Antibody is a Goat Polyclonal antibody against Coronin 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin 3 (CORO1C) Immunogen: abx269520 - C-Terminus: C-RISKLEQQMAKIAA |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 23603 |
| NCBI Accession | NP_055140.1 |
| Alias | HCRNN4,Coronin-3,Coronin-1C,CRN2,CRNN4 |
| Background | Antibody anti-CORO1C |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Coronin 1C (CORO1C) is another member of the coronin protein family with a role in regulating actin filament dynamics. Like CORO1A and CORO1B, CORO1C plays a crucial role in cellular processes such as actin-based movement, endocytosis, and cytokinesis. However, CORO1C is particularly important in the regulation of the immune system, where it modulates the signaling pathways of immune cells, including T cells, and contributes to the response to inflammation. It is also involved in maintaining the structural integrity of immune synapses, which are crucial for the communication between immune cells. Similar to the other coronins, CORO1C's dysregulation can impair immune function and has been associated with conditions that affect immune responses. Understanding the role of CORO1C in immune cell signaling and actin dynamics is critical for advancing therapeutic strategies targeting immune-related diseases.
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