Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133) Antibody

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Description
Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho- CREB1 (S133).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P16220 |
| Gene ID | 1385 |
| OMIM | 123810 |
| Background | Antibody anti-CREB1 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element(CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
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