Cytochrome B-245 Heavy Chain (CYBB) Antibody
312€ (60 µl)
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935106861
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name
Cytochrome B-245 Heavy Chain (CYBB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001378
tested applications
WB
Description
Cytochrome B-245 Heavy Chain (CYBB) Antibody is a Rabbit Polyclonal antibody against CYBB. Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytochrome B-245 Heavy Chain (CYBB) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04839 |
| Gene ID | 1536 |
| NCBI Accession | NP_000388.2 |
| Background | Antibody anti-CYBB |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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