Death Domain-Containing Protein CRADD (CRADD) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Death Domain-Containing Protein CRADD (CRADD) Antibody is a Rabbit polyclonal antibody for the detection of Human Death Domain-Containing Protein CRADD (CRADD).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Death Domain-Containing Protein CRADD (CRADD) Immunogen: Recombinant Death Domain-Containing Protein CRADD (Met1-Leu140) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78560 |
| Gene ID | 8738 |
| NCBI Accession | NP_001307028.1 |
| Alias | RAIDD, MRT34,CASP2,RIPK1,CRADD |
| Background | Antibody anti-CRADD |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
CRADD antibody
RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
Ver Producto
Recombinant Human CRADD
Ver Producto
CASP2 And RIPK1 Domain Containing Adaptor With Death Domain (CRADD) Antibody
CRADD Antibody is a Rabbit Polyclonal antibody against CRADD. The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008].
Ver Producto