Disrupted In Schizophrenia 1 Protein (DISC1) Antibody

Este producto es parte de DISC1 Scaffold Protein
Product Graph
442€ (200 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Disrupted In Schizophrenia 1 Protein (DISC1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432606
tested applications
P-ELISA, WB

Description

DISC1 Antibody is a Goat Polyclonal antibody against DISC1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Disrupted In Schizophrenia 1 Protein (DISC1)
Immunogen: abx269954 - Internal region: C-HSEDKRKTPLKVLE
Host
Goat
Reactivity
Human
Assay Type
Concentration: 0.5 mg/ml
Recommended Dilution
P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
27185
NCBI Accession
NP_001012975.1, NP_061132.2
Alias
DISC1, C1orf136, SCZD9, disrupted in schizophrenia 1, DISC1 scaffold protein
Background
Antibody anti-DISC1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Disrupted in schizophrenia 1 (DISC1) is a scaffolding protein with diverse roles in neurodevelopment, synaptic function, and adult neurogenesis. Originally identified in a Scottish family with a high incidence of schizophrenia, DISC1 has since been implicated in several psychiatric disorders, including bipolar disorder and major depression. DISC1 interacts with multiple molecular partners, influencing signaling pathways involved in neuronal proliferation, migration, and axonal growth. Additionally, it regulates mitochondrial function and intracellular trafficking. Dysfunctional DISC1 has been associated with structural brain abnormalities, synaptic deficits, and altered neuronal connectivity, which are common features in neuropsychiatric disorders. The multifaceted roles of DISC1 in cellular processes and its potential as a biomarker or therapeutic target underscore its significance in neuroscience and psychiatry research.
Related Products
abx269954
Disrupted In Schizophrenia 1 Protein (DISC1) Peptide
Disrupted In Schizophrenia 1 Protein (DISC1) Peptide is a synthetic peptide. This peptide is used in the production of
Ver Producto