Egl Nine Homolog 1 (EGLN1) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Egl Nine Homolog 1 (EGLN1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001065
tested applications
IF/ICC
Description
EGLN1 Antibody is a Rabbit Polyclonal antibody against EGLN1. The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Egl Nine Homolog 1 (EGLN1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9GZT9 |
| Gene ID | 54583 |
| NCBI Accession | NP_071334.1 |
| Background | Antibody anti-EGLN1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
