Epithelial Cell Adhesion Molecule (EPCAM) Antibody
299€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Epithelial Cell Adhesion Molecule (EPCAM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129957
tested applications
WB, IHC
Description
Epithelial Cell Adhesion Molecule (EPCAM) Antibody is a Rabbit Polyclonal against Epithelial Cell Adhesion Molecule (EPCAM).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Epithelial Cell Adhesion Molecule (EPCAM) Immunogen: abx167541 - Recombinant Pig EPCAM (Gln25-Gln265) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Pig |
| Assay Type | Concentration: 0.76 mg/ml |
| Recommended Dilution | WB: 0.01-3 µg/ml, IHC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q75QW1 |
| OMIM | 403163 |
| Alias | ESA,KSA,M4S1,MK-1,DIAR5,EGP-2,EGP40,KS1/4,MIC18,TROP1,TACSTD1,Ep-CAM,Adenocarcinoma-associated antigen,Cell surface glycoprotein Trop-1,Epithelial cell surface antigen |
| Background | Antibody anti-EPCAM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Epithelial Cell Adhesion Molecule (EPCAM) , also known as CD326 or TACSTD1 (tumor-associated calcium signal transducer 1), is a transmembrane glycoprotein prominently expressed on the surface of epithelial cells in various tissues. EpCAM plays a dual role in cellular adhesion and signaling, as well as in the regulation of cell proliferation and differentiation. Originally identified as a marker on cancer cells, EpCAM is also a vital component in normal epithelial physiology, where it participates in maintaining cell-cell adhesion and the structural integrity of epithelial layers. EpCAM has become a major focus in cancer research due to its high expression in numerous epithelial tumors, including colorectal, breast, lung, and ovarian cancers. It is frequently upregulated in cancer, where it contributes to cell proliferation, migration, and invasion, as well as tumor growth and metastasis. Its presence on circulating tumor cells has made EpCAM a promising biomarker for early cancer detection and prognosis. Beyond its role in oncogenesis, EpCAM is involved in regenerative processes in epithelial tissues, influencing stem cell behavior and tissue repair.
Related Products
Pig Epithelial Cell Adhesion Molecule (EPCAM) Protein
Pig Epithelial Cell Adhesion Molecule (EPCAM) protein is a recombinant protein expressed in E. coli.
Ver Producto