Eukaryotic Elongation Factor 2 Kinase (EEF2K) Antibody
208€ (20 µl)
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935106861
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name
Eukaryotic Elongation Factor 2 Kinase (EEF2K) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004139
tested applications
ELISA, WB, IF/ICC
Description
EEF2K Antibody is a Rabbit Polyclonal antibody against EEF2K. This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Eukaryotic Elongation Factor 2 Kinase (EEF2K) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00418 |
| Gene ID | 29904 |
| NCBI Accession | NP_037434.1 |
| Background | Antibody anti-EEF2K |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Human EEF2K (Eukaryotic elongation factor 2 kinase) ELISA Kit
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EEF2K antibody
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
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