Fc Receptor Like 5 (FCRL5) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Fc Receptor Like 5 (FCRL5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx323655
tested applications
ELISA, WB
Description
FCRL5 Antibody is a Rabbit Polyclonal against FCRL5.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc Receptor Like 5 (FCRL5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96RD9 |
| Gene ID | 83416 |
| Alias | Fc receptor-like protein 5,CD307,FCRH5,IRTA2,BXMAS1,CD307e,PRO820,FcR-like protein 5,FcRL5,Fc receptor homolog 5 |
| Background | Antibody anti-FCRL5 |
| Status | RUO |
Descripción
Fc Receptor Like 5 (FCRL5) is broadly expressed on B cells, including plasma cells, and is a key regulator of B cell activation and differentiation. FCRL5 has a unique extracellular domain capable of binding to IgG antibodies, modulating immune signaling pathways. It also contains ITIM motifs and immunoreceptor tyrosine-based switch motifs (ITSMs), enabling it to integrate activating and inhibitory signals. FCRL5 expression is increased in certain B cell malignancies, such as multiple myeloma, where it may serve as a diagnostic marker or therapeutic target.
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