Fc Receptor-Like Protein 1 (FCRL1) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
Fc Receptor-Like Protein 1 (FCRL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432683
tested applications
P-ELISA, WB
Description
FCRL1 Antibody is a Goat Polyclonal antibody against FCRL1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Fc Receptor-Like Protein 1 (FCRL1) Immunogen: abx617206 - C-Terminus: C-SRLRKANITDVD |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 115350 |
| NCBI Accession | NP_443170.1, NP_001152870.1 |
| Alias | Fc receptor-like protein 1FcR-like protein 1,FcRL1,Fc receptor homolog 1,FCRH1,IFGP1,IRTA5,CD307a |
| Background | Antibody anti-FCRL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Fc Receptor Like 1 (FCRL1) is a transmembrane protein expressed primarily on B cells and is a member of the immunoglobulin superfamily. It plays a role in regulating B cell activation and immune responses. The cytoplasmic domain of FCRL1 contains both immunoreceptor tyrosine-based activation motifs (ITAMs) and immunoreceptor tyrosine-based inhibitory motifs (ITIMs), suggesting it can transmit both activating and inhibitory signals. Dysregulation of FCRL1 expression has been associated with autoimmune conditions like systemic lupus erythematosus (SLE), indicating its importance in immune tolerance and balance.
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