Fc Receptor-Like Protein 2 (FCRL2) Antibody

351€ (100 µg)
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935106861
info@markelab.com
name
Fc Receptor-Like Protein 2 (FCRL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx376081
tested applications
ELISA, WB
Description
Fc Receptor-Like Protein 2 (FCRL2) Antibody is a Rabbit Polyclonal antibody against Fc Receptor-Like Protein 2 (FCRL2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Fc Receptor-Like Protein 2 (FCRL2) Immunogen: Synthesized peptide derived from Human Fc Receptor-Like Protein 2 (130-210 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LA5 |
| Gene ID | 79368 |
| Alias | Fc receptor-like protein 2,FCRH2,IFGP4,IRTA4,SPAP1,CD307b,SPAP1A,SPAP1B,SPAP1C,FcR-like protein 2,FcRL2,IFGP family protein 4 |
| Background | Antibody anti-FCRL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Fc Receptor Like 2 (FCRL2) is another member of the FCRL family, predominantly expressed on mature B cells and plasma cells. FCRL2 also contains cytoplasmic ITIM motifs, indicating its role as an inhibitory receptor. It is involved in modulating B cell receptor (BCR) signaling, plasma cell survival, and antibody production. Alterations in FCRL2 expression have been implicated in hematological malignancies such as chronic lymphocytic leukemia (CLL), where it may serve as a biomarker for disease progression and therapeutic targeting.
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