Fc receptor-like protein 3 (FCRL3) Antibody (FITC)
169€ (20 µg)
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Name
Fc receptor-like protein 3 (FCRL3) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx348573
Description
Fc receptor-like protein 3 (FCRL3) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human FCRL3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Fc receptor-like protein 3 (FCRL3) Immunogen: Recombinant Human Fc receptor-like protein 3 protein (122-222 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96P31 |
| Alias | Fc receptor-like protein 3,MAIA,FCRH3,IFGP3,IRTA3,SPAP2,CD307c,Fc receptor homolog 3,IFGP family protein 3,Hifgp3 |
| Background | Antibody anti-FCRL3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Fc Receptor Like 3 (FCRL3) is expressed on B cells, regulatory T cells, and some natural killer cells, functioning as an immune checkpoint molecule. The presence of ITIMs in its structure supports its inhibitory role in immune regulation, particularly in dampening autoimmunity. FCRL3 polymorphisms have been linked to autoimmune diseases such as rheumatoid arthritis and type 1 diabetes, where genetic variants contribute to increased susceptibility. Collectively, the FCRL family represents a critical set of regulators for immune cell function, offering potential therapeutic targets for autoimmune disorders and B cell-related malignancies.
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