Forkhead Box Protein P2 (FOXP2) Peptide
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Description
Forkhead Box Protein P2 (FOXP2) Peptide is a synthetic peptide.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Forkhead Box Protein P2 (FOXP2) |
| Host | Synthetic |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Observed MW | Sequence Fragment: Internal region: C-DEVEYQKRRSQKIT |
| Size 1 | 100 µg |
| Form | Lyophilized Reconstitute in deionized water. |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15409 |
| Gene ID | 93986 |
| NCBI Accession | NP_055306.1, NP_683696.2, NP_683697.2, NP_683698.2, NP_001166237.1 |
| OMIM | 602081 |
| Background | Protein FOXP2 |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors.It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut.The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes.This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development.Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia.Multiple alternative transcripts encoding different isoforms have been identified in this gene.
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