G Protein Coupled Receptor 120 (GPR120) Antibody
442€ (200 µl)
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name
G Protein Coupled Receptor 120 (GPR120) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431028
tested applications
P-ELISA, IHC
Description
GPR120 Antibody is a Goat Polyclonal antibody against GPR120.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: G Protein Coupled Receptor 120 (GPR120) Immunogen: abx615658 - Internal region: C-YSESHQIRVSQQD |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 338557, 107221, 294075 |
| NCBI Accession | NP_859529.2 |
| Alias | FFAR4,PGR4,GPR120,GPR129,G-protein-coupled receptor GT01,GT01,G protein-coupled receptor 120,G protein-coupled receptor 129,omega-3 fatty acid receptor 1,O3FAR1,G-protein coupled receptor GT01,OB10Q,BMIQ10 |
| Background | Antibody anti-FFAR4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
FFAR4, also known as GPR120, is a G protein-coupled receptor activated by long-chain free fatty acids, including omega-3 fatty acids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). FFAR4 is expressed in adipocytes, macrophages, and the gastrointestinal tract, where it regulates metabolism, inflammation, and insulin sensitivity. In adipose tissue, FFAR4 activation enhances insulin sensitivity and glucose uptake, while in macrophages, it suppresses pro-inflammatory signaling pathways, such as NF-κB, reducing chronic inflammation. FFAR4 also promotes the release of gut hormones like GLP-1, contributing to satiety and glucose homeostasis. Dysregulation of FFAR4 signaling is associated with obesity, insulin resistance, and inflammatory diseases, highlighting its role in metabolic and immune regulation. In cancer, FFAR4 activation has shown potential anti-tumor effects by modulating inflammation and cellular metabolism. FFAR4 is being explored as a therapeutic target for metabolic disorders, obesity, and inflammatory diseases due to its ability to mediate the beneficial effects of omega-3 fatty acids.
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