G-Protein Coupled Receptor 125 (GPR125) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
G-Protein Coupled Receptor 125 (GPR125) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432134
tested applications
P-ELISA, WB, IHC
Description
GPR125 Antibody is a Goat Polyclonal antibody against GPR125.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: G-Protein Coupled Receptor 125 (GPR125) Immunogen: abx615536 - Internal region: CTNKSASSFKNS |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 166647, 70693 |
| NCBI Accession | NP_660333.2 |
| Alias | ADGRA3,TEM5L,TEM5-like,PGR21,GPR125 |
| Background | Antibody anti-ADGRA3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ADGRA3, also known as GPR125, is widely expressed in stem cells, reproductive tissues, and certain endothelial cell populations. Like other adhesion GPCRs, ADGRA3 features a GAIN domain and mediates interactions with extracellular matrix proteins. This receptor is involved in stem cell regulation, particularly in germline and neural progenitor cells, and may influence tissue regeneration and repair. ADGRA3 has been implicated in Wnt signaling, contributing to cellular differentiation and development. Recent research highlights its potential role in tumorigenesis and immune cell modulation. ADGRA3's expression patterns and signaling capabilities make it a promising target for regenerative medicine and cancer therapies.
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