Glutaredoxin 1 (GLRX) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Glutaredoxin 1 (GLRX) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004064
tested applications
IHC, IF/ICC

Description

GLRX Antibody is a Rabbit Polyclonal antibody against GLRX. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Glutaredoxin 1 (GLRX)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P35754
Gene ID
2745
NCBI Accession
NP_002055.1
Alias
Thioltransferase-1,TTase-1,GRX
Background
Antibody anti-GLRX
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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GLRX antibody

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Ver Producto