Heparan Sulfate Proteoglycan 2 (HSPG2) Antibody
377€ (100 µg)
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935106861
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name
Heparan Sulfate Proteoglycan 2 (HSPG2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx240009
tested applications
ELISA, IHC
Description
Heparan Sulfate Proteoglycan 2 (HSPG2) Antibody is a Rabbit Polyclonal antibody for the detection of PGBM.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Heparan Sulfate Proteoglycan 2 (HSPG2) Immunogen: heparan sulfate proteoglycan 2 |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | IHC: 1/100 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 469 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P98160 |
| Alias | PLC,SJA,SJS,HSPG,SJS1, PRCAN,HSPG,Perlecan,Basement membrane-specific heparan sulfate proteoglycan core protein,Schwartz-Jampel syndrome 1,chondrodystrophic myotonia |
| Background | Antibody anti-HSPG2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Heparan sulfate proteoglycan 2 (HSPG2), also known as perlecan, is a significant component of the extracellular matrix (ECM) in many tissues, including basement membranes. HSPG2 plays a crucial role in various physiological processes such as cell adhesion, proliferation, differentiation, and migration. It is synthesized as a large multidomain protein and is extensively glycosylated. Perlecan is ubiquitous in the body, present in vascular endothelial cells, the central nervous system, skeletal muscle, and other tissues. Its importance is underscored by its involvement in numerous developmental and pathological conditions, including cancer, cardiovascular diseases, and genetic disorders like Schwartz-Jampel syndrome and Dyssegmental Dysplasia Silverman-Handmaker type.
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