Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF) Antibody

338€ (60 µl)
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935106861
info@markelab.com
name
Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004220
tested applications
IF/ICC
Description
HNRNPF Antibody is a Rabbit Polyclonal antibody against HNRNPF. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | IF/ICC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P52597 |
Gene ID | 3185 |
NCBI Accession | NP_001091678.1 |
Background | Antibody anti-HNRNPF |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Component of the heterogeneous nuclear ribonucleoprotein(hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
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